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Dose and duration are also relevant.
We cured acute leukaemia in mice in 1977 with drugs that we are still using in exactly the same dose and duration today in humans with dreadful results.
Peak plasma and tissue Se concentrations were functions of the dose and duration of MSC treatment.
Dose and duration should be dependent on the level of risk.
Both criteria considered simultaneously the choice of drug, dose and duration of treatment.
The paper's ultimate conclusion was that "further work is needed to define the optimal type, dose and duration of postmenopausal hormone use" for maximizing the protective benefit.
Together, these results suggest that the magnitude (dose and duration) of Dox administration determined the degree of Tat-induced potentiation of cocaine-CPP.
Sodium oxybate dose and duration of therapy were also noted.
The dose and duration of steroids are highly variable.
Associations between frequency, dose, and duration of analgesic use and risk of ovarian cancer were also assessed.
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These changes appear to be dose- and duration-related and are mostly reversible.
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CEO of Professional Science Editing for Scientists @ prosciediting.com