Sentence examples for dose alteration from inspiring English sources

According to our observations, dose alteration of a single gene led to quantitative changes in a large number of proteins.

In contrast, dose alteration of 14 genes resulted in an unequal number of up and down-regulated proteins, though the balance was kept at the level of protein concentration.

An interesting observation was made when we considered proteins that were only altered in both mES_14_Mono and mES_14_Tris: Two thirds of them showed the same change tendency, i.e., either up-regulated in both cell lines, or down-regulated in both cell lines, despite opposite gene dose alteration (trisomy versus monosomy).

Rifabutin levels are decreased by 16%; no dose alteration is required.

Of total medications prescribed (n=1,469), geriatricians recommended withdrawal of 9.8% (n=145) and dose alteration of 3.5% (n=51).

†Includes myopathy with statin treatment, or clinically relevant altered plasma concentration (for example, of digoxin, lithium, ciclosporin, or theophylline), which might require dose alteration or closer monitoring.

To study the effect of gene dose alterations on the cellular proteome, we carried out a proteomic investigation on murine embryonic stem cells that either overexpressed individual genes or displayed aneuploidy over a genomic region encompassing 14 genes.

9– 11 Renal impairment does not require dose alterations.

Approval from the DSMC will be required prior to any subsequent dose alterations.

This will allow us to track changes in medication instruction, such as swapping to 16 hour use or dose alterations.

Plasma clearance of paclitaxel exhibits non-linear kinetics, which results in a disproportionate change in plasma concentration and area under the concentration time curve with dose alterations.