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They started with 334 horse eggs, replacing their nuclei with those of donor cells.
In some cases, it took months for the donor cells to begin working against the tumors.
In the patients with kidney cancer, Dr. Childs and his colleagues used the donor cells in a radically different way.
Another question is whether donor cells last for long when transplanted, or are rejected by the body's immune system.
Researchers have had little success using donor cells to inoculate humans who are going to receive transplants.
The donor cells are dripped into the patient's vein like a transfusion, and the stem cells naturally find their way to the patient's bone marrow.
The importance of the finding, Dr. Kunkel said, is that it confirms that human donor cells can be incorporated into a recipient's muscle fibers.
Rather than using them to rescue the patient from chemotherapy, they reasoned that the donor cells themselves could fight the patient's cancer.
One crucial step is to make suitable donor cells, either from established stores of embryonic stem cells, or by converting patients' skin cells into photoreceptor cells.
If enough donor cells can be delivered efficiently to the muscle fibers in a patient's body, they may provide a treatment for the disease.
Therapeutic cloning could also help in the development of universal donor cells, said Dr. Roger Pedersen, director of the Cambridge Stem Cell Institute.
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