Insights into mammalian Fe-S cluster biogenesis have been confounded by the fact that a dominating paradigm has been developed in the model system S. cerevisiae, in which it was proposed that Fe-S cluster biogenesis occurred or was initiated solely in the mitochondria, but not cytosolic or nuclear compartments (Lill, 2009).
However, the once dominating paradigm of "mono drug mono target" in drug development is now being challenged by the clinical and pharmaceutical people, since the single drug cannot always be effective for the complex diseases (such as cancer and diabetes), which may involve multiple biological pathways and complex pathological process.
Important recommendations on the use of fiber beam column elements for studying existing R/C structures, which do not comply with the flexure dominated paradigm of walls in the most recent code specifications, are provided.
Dominating paradigms, also in basic research, can become closed systems that should be opened by mobility, cross-fertilization, and suitable incentive systems. 5.
While the slavery era may serve as a screen on which current conflicts are acted out, the nation is now freeing itself from the old Confederate-dominated paradigm, and can finally see the period from 1790 to 1865 as a deeply stained but defining era in the history of this strange nation.
We have examined how the chronotope of people with chronic illness, our example being Type 2 diabetes, can differ, often profoundly, from that of the able-bodied, the health practitioner, and the current, dominate research paradigm in health psychology.
Research in perceptual decision making is dominated by paradigms that tap the visual system, such as the random-dot motion (RDM) paradigm.
However, until recently, the field of social cognitive neuroscience has been dominated by paradigms in which participants passively observe social stimuli from a detached "third person" perspective.
>> Research in perceptual decision making is dominated by paradigms that tap the visual system.
In these constructions of the Platform, any anxiety that the lack of a local in-country GAVI or Global Fund presence would automatically lead to WB paradigms dominating the implementation of the Platform were countered by a division of influence: WHO would retain its technical and normative functions; WB its sustainable financing policy and budget frameworks.
Though Caughley did not couch his discussion in terms of national traditions, the small populations paradigm dominated research programs in the United States whereas the declining populations paradigm dominated the Australian tradition.
