Induction of CHIA is via a TH2 specific, IL-13 mediated pathway, and has been implicated in TH2 dominated disorders such as asthma [ 53].
After adolescence, internalizing disorders and substance use disorders dominate externalizing disorders, such as oppositional defiant disorder and conduct disorder [ 3].
Thus contemporary scholasticism is founded on the inherently unstable, perishable material world, which is dominated by disorder and evil as a consequence of Adam's sin.
The observed high comorbidity in our study contradicts the idea of selecting and designing institutions for one dominating disorder.
However, the observed high comorbidity in our study challenges the idea of selecting and designing institutions for one dominating disorder.
We found extensive use in older age groups where osteoarthritis is the dominating knee disorder.
The book, with its sense of all-enveloping menace, shadowy actors and conspiracies reaching to the highest levels of government, tapped into a mounting sense of unease in the United States at a time when political murder and social disorder dominated the headlines.
Therefore, a disorder dominated by a polygenic model will be one in which several common variants of modest effect contribute to risk for disease in each affected individual.
Thus, a disorder dominated by a heterogeneous model is one in which many relatively rare but more highly-penetrant pathogenic variants mediate risk for the disease in the affected population.
In this study, we describe the clinical and imaging features of 12 subjects with a progressive neurological disorder dominated by AOS in the absence of aphasia or other prominent neurological signs.
The overall frequency of K10 scores at or above the clinical cut-off (≥20) is further broken down into anxiety-dominated disorder (K10-anxiety items: 2, 3, 5, 6), depression-dominated disorder (K10-depression items: 1, 4, 7, 8, 9, 10) or a mixed disorder.
