Both ErbB2-positive cell lines showed dominant TRAIL-R2-mediated cell death at low concentrations of scFv scTRAIL, demonstrating that cell surface immobilized scFv scTRAIL exerted membrane TRAIL-like activity, similar to what has been previously described for conventional scFv TRAIL fusion proteins.
11 An understanding of the opposing motion paths (ulnar/radial deviation for the leading, non-dominant wrist; flexion/extension for the trailing, dominant wrist) enables us to understand the mechanism of wrist and hand injuries in golf.
The trailing, dominant wrist moves in a different path altogether, being in neutral at address before moving quickly into maximal extension during the backswing (figure 3) and only moving back into neutral (and ultimately flexion) just before impact.
Dominant candidates do not trail people like Herman Cain and Donald Trump in the polls.
Hillary Clinton drew competition into the campaign trail, chastising dominant corporations for "using their power to raise prices, limit choices for consumers, lower wages for workers and hold back competition from start-ups and small businesses".
Colgate, which never trailed, was dominant.
The best proof of this proposition came in the Philippines, where Facebook partnered with Globe – the smaller of the country's two dominant mobile companies – which trailed its rival's market share by 20 percentage points.
A strong base in relatively untapped markets like India and China are important for the once dominant company, which now trails Hewlett-Packard globally in terms of sales.
They came to talk about business and manufacturing and, of course, to hit hard on the dominant theme of the campaign trail: unemployment and the struggling economy.
Not only has energy been the dominant issue on the campaign trail this summer, it was a central theme at the Democratic National Convention in Denver during the past few days.
For example, somatic mutations in DR5 cause a dominant negative phenotype that blocks TRAIL signaling through DR4 and DR5, but has no effect on Fas signaling [19].
