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These are often referred to as autosomal dominant diseases because of frequent phenotypic dominance of the mutated allele over the wild-type allele during transmission along generations.
Unlike autosomal recessive diseases, autosomal dominant diseases are expressed when only one mutant gene is present.
Inherited cardiomyopathies and arrhythmias are autosomal dominant diseases with an important genetic heterogeneity.
Scientists hope that ribozymes might be effective weapons against other autosomal dominant diseases such as Huntington's disease and glaucoma.
Like almost all autosomal dominant diseases, ADRP wreaks its havoc because one copy of a gene produces a mutant--and damaging--protein, in this case a mutant rhodopsin.
Numerous pre-clinical studies are evaluating RNAi as a novel therapeutic modality in the battle against gain-of-function autosomal dominant diseases, cancer, and viral infections.
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We divided Mendelian disease genes into dominant disease genes (238 hOMIM genes that are known to have dominant diseases-causing mutations) and recessive disease genes (389 genes that are known to have recessive diseases-causing mutations) as annotated by Blekhman et al. (2008).
Huntington's by contrast is a dominant disease.
F.F.I is an autosomal dominant disease, which means you have a one-in-two chance of having the disease if your parent has it.
Like OPMD, it is an autosomal dominant disease, meaning that each child of an affected parent has a 50percentt chance of inheriting it.
Familial hypercholesterolemia (FH) is a heterogeneous autosomal dominant disease.
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