The dominant analysis technique for untargeted metabolomics is chromatography coupled with mass spectrometry (MS) but this method is hindered by a large number of unknown peaks [5] and the limited number of reference spectra available to identify the peaks [6].
The envelope detection or demodulation methods have been established as the dominant analysis methods for this purpose, since they can separate the useful part of the signal from its redundant contents.
In the parlance of stochastic dominance analysis, searching for 5 hours is first-order stochastic dominant over searching for 10 hours; preferring a first-order dominant strategy only requires the assumption that larger benefits are preferred to smaller benefits.
Analysis for dominant model indicated that the variant G allele carriers (GG + GA) may have increased the risk of SLE when compared with the homozygote AA in overall populations and in Caucasian (Overall: OR 1.203, 95%CI.: 1.029 1.407; Caucasian: OR 1.233, 95%CI.: 1.014 1.499), but not in Asian (OR: 1.154; 95%CI.: 0.856 1.557).
We designed and optimised the analysis for a dominant negative Aiolos isoform, but the described method is applicable to any isoform-forming gene.
Inter-group comparisons of genotype frequency differences were performed by regression analysis for codominant, dominant, recessive and log-additive models of inheritance.
In addition, three studies [48], [61], [68] that only provided the total number of variant genotypes (Arg/Ser and Arg/Arg) were included in the analysis for the dominant model but not for other genetic models.
Euclidean pairwise genetic distances were calculated in GenAlEx 6.2, which allows a common pathway for subsequent statistical analysis for both dominant AFLP markers and codominant SSR markers (Maguire et al. 2002).
In dominant component analysis (DCA), for each pixel approach, the best AM-FM demodulation estimates are selected from the bandpass filter that produces the largest IA estimate.
Genotype frequency differences were evaluated by regression analysis for allelic, genotypic, dominant and recessive models of inheritance.
Additionally, results from a sensitivity analysis for different threshold values of dominant design call for adjusting a binary definition of dominant design with different threshold values depending on the effects under study.
