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That's its really defining feature: a steep domed cap with a nipple on top.
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The oversize '60s-era domed caps added to the high drama.
rPrP fibrils at 0.1 mg/ml were heat-treated in PBS, pH 7.4, in the presence of 5% NBH or 5 mg/ml BSA (Sigma, #A3294) and 0.1% Triton X-100 using the following procedure: 50 μl aliquots in thin-wall PCR tubes with domed caps were placed into the PCR machine and subjected to 5 cycles of 1 min incubation at 80°C followed by 1 min incubation at 37°C.
Following assembly into an undecamer complex, the β β β α structure forms a round "stem" base and the binding groove creates a "domed-cap" with a positively charged channel running along the upper surface to accommodate DNA (Kagawa et al. 2002).
The inside, perhaps 50 feet across, is capped by a high domed roof like that of an old-time merry-go-round.
The moment she first saw the domed ice cap of Antarctica, during a visit to the Hodgeman Islands last week, she said it took her breath away.
Usually a metal boss (a domed metal cap) was set in the middle of the shield with nails.
But the domed roof still needs waterproofing.
A domed roof of clay was its most distinctive difference.
Its domed ceiling is modeled after Monticello.
A domed ceiling descended, guaranteeing a captive audience.
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