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The amino acid sequences of the domains (underlined) are from Strayer et al. [ 42 ].
The amino acid sequences of the domains (underlined) are from Wang et al. [ 40 ].
The amino acid sequences of the domains (underlined) are from Somers et al. [ 43 ].
Similar to dysferlin, dystrophin contains essential and less essential domains, underlined by the finding that patients with in-frame mutations in the redundant central domain suffer from a milder disease called Becker muscular dystrophy.
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Interestingly, reasoning experts struggle with solving problems outside their own domains underlining the need for sufficient domain knowledge [ 8- 12].
Further increase of the electrical coupling leads to the appearance of the IP pattern (see vertical line area, Fig. 2C1), which coexists with AP in some parameter domain (underlined surface Fig. 2C1).
Also see corresponding Video 2. DOI: http://dx.doi.org/10.7554/eLife.06807.003 10.7554/eLiFigure07.004 Figure 1 figure supplement 1. Lsm4 has a prion-like C-terminal domain (underlined) that is enriched for asparagines (N) and glutamines (Q) and contains hydrophobic residues (L, V, I, M, F).
Such cross-subsidization is clearly at odds with a market-led approach and a comparison with the housing domain underlines the peculiarity of these financial arrangements.
The importance of the 'communication' domain underlines the necessity of conceiving the teaching of medication prescribing in a patient-centred manner, with emphasis on patient education.
Finally, the presence of MKRN1's four C3H zinc finger RNA-binding domains underlines our contention that MKRN1 is a genuine RNA-binding protein.
An alignment of the LRR domains underlines the high degree of similarity between the three LRX proteins with 95% (LRX3 compared to LRX4), 86% (LRX3 compared to LRX5), and 85% (LRX4 compared to LRX5) (Additional file 1).
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