This means that approximately 180 million of the 275 million domains are active in the true sense of the word.
All domains were active except Lam4S1, which was less active in ∆ysp2.
All variants except the two mini-catalytic domains were active against the synthetic substrate.
A3B contains two cytosine deaminase domains (CD1, CD2), and there are conflicting reports about whether both domains are active.
LePRK1 and 2 are closely related and their E. coli-produced kinase domains are active kinases and autophosphorylate (Muschietti et al. 1998).
Assuming that both helical hook domains are active and, in accordance with the situation for SinR, SinI and SlrA, the hetero-oligomeric interactions are of higher affinity than the self-interactions, SlrR possesses the potential to form both "open" and "closed" complexes (Fig. 2).
They may have nothing to do with whether an adjacent domain is active or repressed; they may only prevent the spread of activation or repression.
You will need to wait until your domain is active before you can continue.
The C-terminal catalytic domain is active independently of the localization conferring N-terminal part, which is also termed 'CTS' (cytoplasmic, transmembrane, stem).
We have demonstrated that the survival effect of dermcidin, potentially mediated via the calcineurin-like phosphatase domain, is active in cells known to respond to glycosylated PIF.
