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For positive filtration (i.e. selection), the domain origin "surechem.org" gives 54 processed patent document links and "ebi.ac.uk/" returns just 19 links to the Hinxton databases.
Our alternate domain definitions provide differing perspectives towards domain origin from a few general principles.
Since real evidence of domain origin is either unattainable or incomplete, we chose not to limit ourselves to a single optimum domain definition.
To identify the domain origin of the protease resistant fragments we previously used a series of C-terminally truncated CFTR constructs with stop codons behind each subsequent domain [24].
Instead, we treat domain definitions in 3 categories; two of them ("by sequence" and "by structure") represent different plausible mechanisms of domain origin based on the same evolutionary considerations.
Our analyses also infer two instances of de novo domain origin within the KLF/SP gene family (fig. 6).
Similar(53)
Finally, the last section details the patterns of domain origins at different nodes in the context of protein evolution.
WorldVistA, thanks to its public-domain origins, costs about one-tenth of what a proprietary system does for a license fee and a support contract.
Let (x=0) be an equilibrium point for system (19), and let (Dsubset R) be a domain containing origin.
The color of the nodes encodes the domain of origin (i.e., cyber, biometric, biographic, and psychological), which is reinforced with a symbolic representation when the user selects a path.
It deals with unfamiliar concepts, whose clarification took a long time even within their domain of origin" [9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com