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Note the additivity at the boundary vs the sub-additivity at the core, anterior domain of the pattern.
We have studied SNPs in the NACHT domain of the pattern recognition receptor NOD2 associated with BS and EOS to determine the molecular basis of disease.
Although diverse in overall amino acid sequence (only ≍50% sequence identity between PMV family members) all V proteins share a conserved cysteine-rich C-terminus that interacts with the RNA helicase domain of the pattern recognition receptors (PRR) MDA5 and LGP2.
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For instance, the effective domain of this pattern could broaden by the following modulations: decreasing the external electric potential field, decreasing the electric double layer thickness, or increasing the temperature difference between inlet flow and walls.
The alignment of the DBL2X domain shows the pattern of interspersed conserved and variable sequences previously seen in the VAR2CSA domaindomain [40].
Taken together, this study extends the domain of the genome-wide pattern of rapidly evolving reproductive genes from animal systems to fungi.
We report that prediction is correct if domains of the simulated pattern overlap with those observed experimentally (see Additional files 2, 3, 4, 5).
Based on the number of WRKY domains and the pattern of the zinc-finger motif, the WRKY superfamily of plant TFs were classified into three groups (I-III) in Arabidopsis thaliana [ 3], rice (Oryza sativa) [ 4], grape (Vitis vinifera [ 5] and poplar (Populus trichocarpa) [ 6, 7], respectively.
The predicted secondary structure indicates that this is a globular domain, however, the pattern of amino acid residue conservation does not seem to suggest an enzymatic function.
Members of Group 1 typically contain two WRKY domains, while most proteins with one WRKY domain belong to Group 2. Group 3 proteins also have a single WRKY domain, but the pattern of the zinc-finger motif is unique.
Based on the number of WRKY domains and the pattern of the zinc-finger motif, WRKY proteins can be divided into 3 different groups in Arabidopsis [ 20].
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