On the other hand, Domain 1 (Scope and Purpose), Domain 3 (Rigour of Development) and Domain 4 (Clarity of Presentation) generally scored highly, which suggests that the testers all considered that they well explained.
The AGREE II protocol consist of 23 different items organised in 6 domains: domain 1 = "Scope and Purpose" (items 1 3); domain 2 = "Stakeholder Involvement" (items 4 6); domain 3 = "Rigor of Development" (items 7 14); domain 4 = "Clarity of Presentation" (items 15 17); domain 5 = "Applicability" (items 18 21); domain 6 = "Editorial Independence".
Domain 4 ("Clarity of Presentation") had the second-highest mean quality score (80.6%), with 9.3% SD.
Domain 4: Clarity of presentation Item 15 The recommendations are specific and unambiguous.
For domain 4 ("Clarity of Presentation"), the overall mean score was "acceptable" with a mean score of 73.9%.
Domains with the highest quality were "clarity of presentation" (domain 4) and "scope and purpose" (domain 1), as both scored over 70%.
When comparing the scores of each domain across guidelines, "Scope and Purpose" (domain 1) and "Clarity of Presentations" (domain 4) achieved the highest results, with a total domain score of 86.8 ± 3.7% and 80.6 ± 9.3%, respectively.
These similarities were expressed through the domains of symptom presentation, childhood experience, medication treatment issues, impacts in adult life and across the life cycle, addictive and risk-taking behavior, work and productivity, finances, psychological and social impacts.
When comparing the scores of each domain across guidelines, "Clarity of Presentations" (domain 4) and "Scope and Purpose" (domain 1) achieved the highest results, with a total domain score of 73.9% ± 11.2% and 71.1% ± 18.7%, respectively.
The assessed guidelines performed best in the domains of 'clarity of presentation' and 'scope and purpose', which was consistent with the findings of a systematic review for recent hypertension CPGs, 39 five priority diseases' CPGs within Southern Africa 40 and endocrine CPGs in North America.
The least difference was seen in the 'clarity of presentation' domain and the greatest difference in the 'editorial independence' domain.> -wrap-foot> > -wrap-foot> Maximum score for each domain is shown in square brackets.
