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Three of the four receptors comprise an extracellular amino-terminal domain to bind corresponding ligands (for example, EGF to EGFR; ligands to HER2 are not known) and an intracellular carboxyl-terminal domain lodging a tyrosine kinase with the exception of HER3.
Similar(59)
The cpRAS domain is lodged within multiple repeats of the macroglobulin-like domain; this part is not described or analyzed correctly.
The ADR1a domain is lodged between ribosomal proteins uL22 and uL23 and ribosomal rRNA helices H23, H24, and H50 and is located a few angstroms deeper in the exit tunnel in the cryo-EM reconstruction than in the ensemble of folded structures seen in the 140 K molecular dynamics trajectory.
The HDX data show that the VPS15 HEAT-WD40 linker is essentially completely disordered, yet the WD40 domain is firmly lodged in the complex in all class averages.
The friend finds other lodging.
Convenient lodging.
New lifts, lodging, trails and snowcat rides.
We arranged lodging but drove ourselves.
Do-gooders established lodging houses for newsboys.
I'm lodging only one complaint.
And prepare to shell out for lodging.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com