Sentence examples for domain has remained from inspiring English sources

The evolutionary history of the prion protein C-terminal domain has remained a mystery as no other protein for which high-resolution structures have been determined contains the prion protein fold.

A large ρ value (ρ≈1) indicates that the associated breakpoint is located far from a domon midpoint (i.e. close to or beyond the domon boundary), and thus that the protein domain has remained structurally intact, or mostly so, during recombination.

Despite numerous experimental and simulation studies the detailed physical origin of how cholesterol is unique in promoting the formation of the liquid-ordered phase and what is the in-plane membrane structure emerging from the interactions of cholesterol with other lipids in the Chol-rich domain have remained unresolved [19], [20], [28].

The molecular function of fic (filamentation induced by cAMP) domains has remained elusive until recently.

However, the role of PI3K (III) in the regulation of protein localization at different membrane domains has remained unclear.

Since their first systematic description more than a decade ago, the function of these domains has remained unresolved [ 11- 13] with one possibility being that they represent downstream consequences of events at the DNA level (i.e. broadly neutral in functional terms).

The core function of the ankyrin/spectrin duo in patterning membrane micro-domains has remained unchanged throughout evolution, and thus the amino acid sequences of ANK repeats and the spectrin-binding domain of ankyrins are highly conserved (Wang et al., 2012).

In the case where loss of a domain was suspected, we conducted an extensive sequence analysis to rule out the possibility that these domains had remained undetected either due to a frame-shift or inadequate exon-intron splicing of the gene and thus inappropriate translation, preventing recognition by PROSITE [ 51].

Since the early days of the Web, the dot-com extension (the.com part of a domain name) has remained the extension that's most recognized by consumers and most coveted by businesses.

Given the diverse locations of the sensory elements, which are located on both extracellular and intracellular domains, it has remained unclear how signals that are detected by the various sensors are transmitted to the common C-type gate.

Although many AR domains have been crystallized, the AR domain of IκBα has remained resistant to crystallization except in complex with its binding partner, NF-κB.