Sentence examples for domain comprised of a from inspiring English sources

The N-terminus of EBNA1 consists primarily of a 239-amino acid domain comprised of a Glycine-Glycine-Alanine (GGA) repeat region.

The TPR domain is a protein-protein interaction domain, comprised of a loosely conserved 34 amino acid sequence that is repeated several times [7].

PC-1 has a very large extracellular domain comprised of a novel combination of protein-protein interaction domains, 11 transmembrane domains and a short intracellular C-terminus containing a coiled-coil motif that mediates an interaction with the PKD2 gene product, Polycystin-2 (PC-2) [2] [3].

One group of genes attracted our attention, because upon closer inspection it became apparent that these genes had an amino-terminal domain comprised of a VWA domain followed by a region that has good similarity to the first part of the Hint domain, i.e. in particular motifs A and B. This observation was intriguing given that in Nematostella Nv 200640 a Hedge domain is followed by a VWA domain.

It consists of an extracellular domain comprised of an Ig-like V-type domain and two Ig-like C-type domains, a single membrane-spanning domain, and a cytosolic tail [ 3].

Alignment of deduced BTPC sequences from various monocotyledon and dicotyledon species places Ser of COS BTPC in a particularly divergent domain comprised of an approx. 140 residue insertion, a unique structural feature of BTPCs [ 7].

JAM-A is a member of the immunoglobulin superfamily of proteins and contains an extracellular domain comprised of two Ig-like domains, a single transmembrane domain, and a short cytoplasmic C-terminal domain with a PDZ binding motif that is important for the interaction with tight junction scaffolding proteins.

They all consist of a highly similar N-terminal membrane binding domain composed of 24 ankyrin (ANK) repeats, a spectrin-binding domain comprised of two ZU5 domains, and a UPA domain followed by a death domain (DD) and a variable C-terminal regulatory domain (Bennett and Lorenzo, 2013).

Early studies showed that pp32, through a specific domain comprised of ∼25 amino acids, acted like a tumor suppressor by inhibiting K-ras, a mutant p53, c-jun, E1A, E6, and E7 [13], [13].

FIR is a 542-amino-acid protein possessing a central nucleic acid-binding domain comprised of two RRMs, and an N-terminal domain that represses activated, but not basal, c-myc transcription.

Their molecular architecture features a catalytic domain, unrelated to that of all PKC family members, and a large inhibitory, regulatory domain, comprised of two Zinc fingers, and a pleckstrin homology domain.