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In our segregation analysis, p.A152T was absent in the healthy 69-year-old sibling of the proband, suggesting that p.A152T does segregate with disease in this family.
When the ESB does segregate into each daughter nucleus, this inheritance requires cohesion, as knockdown of cohesin subunits leads to an increase in switching frequency among BESs (Landeira et al., 2009).
The similarities between the pig and chicken loci are small, but the SNP does segregate with the high- and low-growth haplotypes in our population observed from our sequencing study.
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Firstly, molecules at the T cell IS do segregate according to size [15], [16], [24], although active, cytoskeletally-driven transport processes are also involved [25].
Instead, they did segregate from the endogenous IF system when transfected into vimentin- or desmin-containing cells [ 13].
All these differences notwithstanding, closely related families do segregate between these two senses, gustatory T2Rs vs. olfactory V1Rs, and T1Rs vs. V2Rs, respectively.
However, when QTL did segregate across breeds, the multibreed analysis refined QTL to smaller genomic regions, allowing a small number of potential candidates to be identified.
If these candidate genes do segregate for anthocyanin levels, gene-based marker-assisted selection or even cisgenics could be used in breeding programmes.
Minicells are produced by bacteria defective in cell division; they lack chromosomal DNA, but plasmids do segregate into them and continue to be metabolically active.
Slightly deleterious mutations segregate at lower frequencies than neutral alleles, and consistent with the idea of segregating deleterious amino-acid mutations, replacement polymorphisms do segregate at lower frequencies than synonymous mutations in D. miranda (Table 1).
Our results demonstrate that within breed analyses actually have more power to detect a higher proportion of the variation but multibreed GWAS results in the more precise mapping of the QTL that do segregate across breeds.
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