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The decrease in the assayed proteasome activities does not necessary implicate an in vivo repression of the overall UPP activity.
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Nevertheless, the binding capacity of antibodies on whole PrPc does not necessary parrallel the neutralizing activity, which could implicate specific epitopes, and thus not predictive of in vivo protection.
But new doesn't necessary mean young.
"Being physically present does not implicate you of a crime".
A speaker who utters (2a) ironically does not implicate (2c).
But a parallel statement like "John supports someone" does not implicate "John does not support himself".
Syria's civil war does not implicate any of Washington's traditional Middle Eastern interests, most importantly Israel and oil.
Surprisingly, the PKC pathway does not appear to be implicated.
"The asterisk doesn't implicate Barry," Idelson said.
"An off-duty nature doesn't implicate police activity," Taylor said.
But yet we have this idea that we can kill someone in a way that doesn't implicate us.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com