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Second, the available evidence does not allow recommendations to be made for, or against, investments in a particular model of TVET.
Current evidence indicates that n-3 LCPUFA may also affect mood, behavior, and overall immune function, but the evidence does not allow recommendations regarding an exact dose.
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235 identified, 3 selected, 2 rated, 2 included Clinical practice Lack of evidence does not allow recommendation of use of synthetic graft for anterior cruciate ligament reconstruction.
The panel agreed on the potential benefits of synthetic grafts in ACL reconstruction; the lack of evidence, however, does not allow recommendation of use of such materials, and further investigations to assess their efficacy and safety are needed.
The current evidence base does not allow specific recommendations to be made on how best to incorporate greening into an urban area.
Vasopressin has been used in rare cases, but the low sample size of these studies does not allow particular recommendations.
Despite large improvements in our understanding of prostate cancer risk factors in the past two decades, present knowledge does not allow definitive recommendations for specific preventative behavioral interventions.
Therefore, it is not surprising that all three existing Cochrane reviews on the pharmacologic treatment of tics in TS [ 51, 186, 189] came to the same conclusion, i.e., that the evidence for efficacy and safety of the studied drugs does not allow firm recommendations.
Finally, the limited evidence of increased risk among patients with HER2-positive tumours <1 cm in size without axillary nodal involvement does not allow definitive recommendation regarding anti-HER2 therapy in this group.
Despite its low cost and high compliance, the low eradication rate does not allow the recommendation of the triple therapy with azithromycin as an adequate treatment for H. pylori infection.
A recent meta-analysis of 15 single-arm case series in patients with oligometastatic disease concluded that local treatment of metastases in this setting may be promising but that the low level of evidence does not allow its recommendation as standard of care [ 40].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com