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We confirmed that S776A does not affect substantially the ability of Atx1 to recognize UHM domains and that S776A binds U2AF65 UHM with affinities comparable to the wild-type.
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In summary, the simultaneous inactivation of the pykA, pykF, and ppsA genes in PB12 did not affect substantially either the µ or the qGlc+Ace compared with PB12.
Varying the levels of therapeutic coverage and systematic noncompliance (Table 1) did not affect substantially the projected health impact of annual or biannual CDTI (Table 4).
Of note, freezing does not affect gene expression substantially.
Some of these studies explicitly note that the choice between self-reported or adjusted BMI does not affect the results substantially [ 11, 12, 16].
However, the mutation I25C does not affect the gating parameter substantially.
Assuming a negative correlation did not affect power substantially.
Exclusion of individuals with a family history of ALS, bulbar onset, or diagnosis > 1 year before enrollment did not affect results substantially.
Furthermore, trunk fat percentage adjustment did not affect these associations substantially (data not shown).
Dietary supplement intake did not affect these values substantially.
However, again this did not affect the outcome substantially (Table 2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com