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How does deficiency in specific types of macroautophagy, such as mitophagy, nucleophagy, lipophagy and so on, impact neuron physiology?
The authors show that deficiency of both Cln1 and Cln5 genes leads to a more severe NCL phenotype in mice than does deficiency of either gene alone.
Inefficient phagocytosis of used outer-segments by RPE leads to sub-RPE accumulation of oxidized lipids as does deficiency in key lipid scavenger receptors such as CD36 [ 11, 12].
Similar(57)
First, do deficiencies of the rDNA, the known pairing centers of the X and Y in male meiosis I, affect chromosome pairing and segregation?
What does iron deficiency do to the body?
What it does: A deficiency has been linked to fatigue, weakness and poor memory.
Why does APTX deficiency lead to neuronal cell death?
Does merlin deficiency in neurons contribute to NF2-related schwannoma formation?
So how does MMR deficiency confer an advantage on cells in vitro?
Indeed, a deficiency in BEIIb induced a more pronounced phenotype than did a deficiency in either BEI or BEIIa [ 3, 12, 13].
(A ) SEC24A deficiency does not cause hypocholesterolemia in the setting of APOE deficiency.
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