In this study, we take this finding a step further by documenting that low insulin sensitivity is present already 5 years before the demonstration of i-IGT.
Furthermore, it is well documented that the degree of fibroglandular tissue density is inversely correlated with mammographic sensitivity.
It has been well documented that the fungal cell wall is an important obstacle to nucleic acid extraction and that the effectiveness of the cell lysis and DNA extraction highly influences the sensitivity of PCR assays [ 17, 18].
Vessby et al. documented that insulin sensitivity was impaired by 10% in healthy individuals who receive an isoenergetic diet containing a high content of saturated fatty acids for 3 months.
It is not definitively known how the timescale of postnatal development in mice relates to that of humans, but it is well documented that sensitivity to SIDS in humans decreases 4 months after birth.
It is well documented that cells have various sensitivity length scales [4 6] and respond to local macro-, micro-, and nano-scale patterns of chemistry and topography differently [2].
It is well documented that probe specificity and sensitivity depend on multiple factors including uniqueness, GC content, steric hindrance, and distance from the 3' end of the ORF [ 13, 14].
Several studies have documented that self-sampling has similar sensitivity to physician-obtained sampling to detect HPV DNA, suggesting that it is a viable screening option and may be a suitable alternative method for studies on HPV transmission and vaccine trials [ 24, 25].
Specifically, a specificity ranging from 100% [ 11] to 80.4% [ 22] has been documented in lymph nodes of patients with early-stage cervical cancer, while the use of an alternative cytokeratin such as CK20 documented that qRT-PCR of CK20 exhibits higher sensitivity than histopathological methods [ 12].
Thus, real time PCR is recommended for future studies to verify the contradictory findings reported by (Blagodatskikh et al., 2010) who documented that SRY gene showed ten times higher sensitivity than DYS14 gene.
