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Conclusion: Empirical administration of piperacillin-tazobactam 16 g day by continuous infusion should be appropriate for most critically ill patients without renal impairment, although patients with very high CrCL ≥ 200 ml min remain at risk of empirical or documented target non-attainment.
Other RCMP intelligence documents obtained by VICE name the Unist'ot'en Camp explicitly, while their annual direct action workshops are a documented target of RCMP surveillance.
SLE patients also have correspondingly high levels of SOCS1, a documented target for miR-155.
The German health care system provides inpatient rehabilitation for patients who have documented target organ damage, particularly after having experienced a CV event such as acute coronary syndrome (with or without interventional or surgical revascularization) or after such an elective intervention without a previous acute event.
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Those populations predating in South African waters have been documented targeting smaller shark species for their livers.
How well the program adhered to its documented targeting design and how effective this design was in reaching the poor is also examined.
The researchers report that when they exposed human diffuse B-cell lymphoma cells to a panel of drugs, the algorithm identified previously documented targets for 70% of the tested compounds.
In addition to these previously documented targets, RAE also identified frequent deletion of 17q11.2 containing NF1 (neurofibromin 1).
The predicted gene targets were compared to documented targets of sRNAs from other bacteria.
Consistent with the hypothesis that down-stream effects of RELA may be contributing to indirect changes in expression levels, we found that a number of the genes differentially expressed after miR-7 transfection are documented targets of NF-κB regulation.
For example, while CD4 targeting nanoparticles may be useful in systemic T-cell targeting, unmodified liposomes have been documented to target lymphoid tissue due to their size and drainage into lymphatic vessels [43], [44], [45].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com