Sentence examples for documented regulations from inspiring English sources

We constructed the yeast transcriptional regulatory network (TRN) from the documented regulations in YEASTRACT [ 81], consisting of 48,082 interactions between 183 transcription factors (TF) and 6,403 target genes (TG).

To generate the regulation matrix, the YEASTRACT database (http://www.yeastract.com/) [ 24] was solicited, in which the differentially expressed genes identified by the RNA-seq analysis were searched against all of the transcription factors (TFs) in the YEASTRACT database (only documented regulations with direct or indirect evidences were taken into consideration).

A TF's target genes are defined as those genes (i) that are known to be regulated by the TF from the TF-gene documented regulation evidence (retrieved from YEASTRACT database [ 18]) or (ii) whose promoters contain the binding sites of the TF (retrieved from SwissRegulon database [ 19]).

Second, the TF-gene documented regulation data was downloaded from YEASTRACT database [ 18], which deposited the documented regulation evidence (from the ChIP-chip and TF knockout experiments in the literature) between TFs and their target genes.

First, yeast is the only organism which has more than 206000 TF-gene documented regulation data available.

Our method is used to infer the cooperativity between two yeast TFs by integrating the TF-gene documented regulation, TFBS and nucleosome occupancy data.

In this study, we developed a novel method to infer the cooperativity between two TFs by integrating the TF-gene documented regulation, TFBS and nucleosome occupancy data.

In this paper, we developed a method to infer the cooperativity between two TFs by integrating the TF-gene documented regulation, TFBS and nucleosome occupancy data.

Based on the documented regulation associations between TFs and genes in the YEASTRACT database, this study has shown that the proposed RS measure is a good co-regulation indicator.

Here, we documented regulation of two genes which have potential influence on S. aureus colonization; cysteine extracellular proteinase (scpA) and von Willebrand factor-binding protein (vWbp, encoded on SaPIbov5).

The useful TF-gene documented regulation data [ 29], which provide the experimentally validated regulatory relationships between TFs and genes, are collected from more than 1300 published papers by the team of the YEASTRACT database [ 18].