Immunotoxins have documented potential as a cancer treatment due to their extreme potency; a single toxin molecule delivered to the cytosol may be sufficient to kill a cell.
We utilised the PA derivative 4-CPA in the present study because of its documented greater potency in terms of its differentiation-inducing activity in comparison with the parent compound (Pineau et al, 1996) and because of its ease in treating animals in vivo (see below).
Aflatoxins are well documented as cancer potency factors as 4.6 28.2% of annual hepatocarcinoma cases worldwide are caused by these toxins [23, 24].
Omalu et al., [130], also documented the antioxidants potency of maggots of the blowfly (Lucilia robineau) excretion/saliva extract with DPPH free radical scavenging activity of (IC50 of 152.66 μg/mL) compared with 108.99 μg/mL of L-ascorbic.
These results provide new evidence that immobilized BPs have positive effects on implant fixation in osteoporotic bone, in addition to their well-documented potency to inhibit implant loosening in normal bone.
Our previous work (Chen et al., 2008) has documented the relative potencies of a series of GluN1 (glycine site) full and partial agonists for each of the four NMDA receptor subtypes.
Several reviews of the literature have documented the prevalence and potency of PTSD among first responders; the value of these extant reviews is considerable.
As one example, genetic variability for iAs biotransformation (biomethylation) as a potential factor in its carcinogenic potency has been documented (Chung et al. 2002; Vahter 2000; Yu et al. 2003).
Year-round, monthly assessment of waste waters by bioassays documented estrogenic, androgenic and dioxin-like potency as well as cytotoxicity in influent waters of the WWTP and allowed characterization of seasonal variability of these biological potentials in waste waters.
The potency of cefditoren has been well documented to include broad coverage against both Gram-positive and Gram-negative organisms including species causing community-acquired respiratory tract infections.
The osteogenic potency of erythropoietin (EPO) has been documented.
