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Therefore the increase of SPARC induced by TKIs could be related to the well documented modification of the bone metabolism observed in IM treated patients.
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The most documented modifications contributing to this phenotype involve profound modifications of cell-wall biosynthesis including increased cell-wall thickness, cross-linking, or accumulation of cell-wall components [ 11, 27].
This procedure documented modifications and aimed to uncover sites which automatically set the current date as the 'last update', thus leading the Internet user to believe that the site is current and state of the art.
We also document modifications in soil temperature, rainfall-runoff responses, and erosion potential at these points that would allow this feedback to occur and create upslope migration of channel heads.
Previous studies have documented epigenetic modification of CpG, CpNpG and CpNpN nucleotides with 5-methylcytosine (5 mC) in retroelement-dense regions of many plant genomes, including triticale [ 41- 43].
A study of endometrial biopsies from LNG-IUS users explored the local effect on the endometrium and documented significant modifications in endometrial vascularization, with a decrease in mean vascular density and an increase in mean vessel area [ 16].
Therefore, the sediment record at Eirik Drift documents modifications in pathways and intensity of the WBUC.
Thus an important task to allow incremental validation is being able to infer, based on the set of document modifications, which segments of the document need to be further validated.
Recent studies have documented that appropriate modification of stroke risk factors can lead to a substantial reduction in stroke incidence.
Methods of data analysis were specified through preliminary discussion and documented using a modification of the Cochrane Review Group's data extraction template.
Assessment of these changes to oral anatomy and feeding kinematics in relation to terapontid trophic diversification would be a valuable complement to the role of intestinal modification documented in this study.
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