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As shown in Fig. 4C, both Gfi1−/− and Gfi1+/+ HSC divided in the presence of SCF & IL7, documented by a decrease in fluorescence intensity.
After four weeks of stress, more than 90% of stressed rats showed signs of anhedonia as documented by a decrease in sucrose preference compared to nonstressed controls (i.e., <50% of sucrose consumption compared to nonstressed controls).
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Effects on bone resorption start within 12 h, as documented by a rapid dose-dependent decrease in urinary and serum N-telopeptide levels.
At doses of 0.5 and 1 µM, doxorubicin had a pro-apoptotic effect documented by a dose-dependent increase in ssDNA positivity and decrease in SA-b-gal positivity.
The morphed graphene nanostructures are documented by a thorough characterization using HRTEM, XRD, and spectroscopies.
Deposition of the B0.81C0.19 film with high hardness (28 GPa) improves the corrosion resistance of the M2 steel substrate by four orders of magnitude, documented by the decrease of the corrosion current from 3 × 10− 6 A/cm2 to 8 × 10− 10−A/cm2.
Indeed, lung CSCs lose their stemness features, as documented by the decrease in ALDH and the downregulation of both Nanog and Oct-4 genes.
In the same time, a significant increase in apoptosis was recorded: those data point out that microgravity rescues CSCs from their relative quiescent state, inducing CSCs to lose their stemness features, as documented by the decrease in ALDH and the downregulation of both Nanog and Oct-4 genes.
Partial response was documented by physical examination (decrease in size of the subcutaneous abdominal mass and bilateral inguinal nodes) and by CT (decrease in size of all known lesions and no new lesions).
Prolonged incubation probably results in degradation or ejection of VHCDR3 by the cells, as documented by the rapid decrease of MFI and percentage of positive cells at 72 h (Fig. 2A).
As expected, forced expression of mPGES-1 in LNCaP cells promoted an increase in PGE2 production, cell growth and development of the mesenchymal phenotype as documented by E-cadherin decrease (Supplementary Figure 4B, C, D and E).
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