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Because of the relatively late occurrence of MI in the natural history of CAD, we focused on a selected population of high risk patients with angiographically documented, advanced CAD.
Patients were required to have histologically or cytologically documented advanced solid tumours refractory to conventional therapy or for whom there are no standard therapies.
Eligible patients had histologically or cytologically documented, advanced (stage IIIb with supraclavicular lymph node metastasis, malignant pleural or pericardial effusion or stage IV) or recurrent nonsquamous NSCLC.
Patients were eligible if they had histologically or cytologically documented advanced solid malignancy, refractory to standard therapy or for which conventional therapy was not effective.
Although explanations for SES differences in survival are not well documented, advanced stage at diagnosis (often associated with screening behavior) has been the most cited explanatory factor [ 45] and there is increasing evidence of inadequate breast cancer treatment and follow-up care being given to patients in lower SES groups [ 45].
Although explanations for SES differences in survival are not well documented, advanced stage at diagnosis has been the most cited explanatory factor [ 32, 33] perhaps because of screening disparities among women age 40 to 79 years [ 34] and increasing evidence suggests inadequate breast cancer treatment and follow-up care among patients in lower SES groups [ 33].
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Furthermore, an increase in depressive and anxiety symptoms from the time of CD diagnosis was also observed, even if no further increases were documented advancing with age.
The primary objective of this study was to identify and document advanced melanoma cases where longer-term survival of at least 3 years was observed, in one clinician's experience.
*Discussion, no wishes (n=3); advance care planning discussion card only (n=8); documented advance care plan (n=14).
For the US, undersecretary of state Ellen Tauscher said the document "advances President Obama's vision" of a world free of nuclear weapons.
Several patterns of gene silencing have been documented in advancing prostate cancer.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com