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Concerns regarding the reliability of biomedical research outcomes were precipitated by two independent reports from the pharmaceutical industry that documented a lack of reproducibility in preclinical research in the areas of oncology, endocrinology, and hematology.
The Directors Guild of America was issuing similar reports about directors back in the 1990s, and last year documented a lack of diversity among directors of prime-time episodic television.
The study, published last week in PLOS ONE, supports what many educators have observed and earlier studies have documented: A lack of confidence in mathematical ability, not mathematical capability itself, is a major factor in dissuading female students from pursuing STEM.
Furthermore, this study documented a lack of health education material available to address these knowledge gaps.
Other researchers also documented a lack of funding and required inputs as a hindrance to the uptake of evidence [ 64].
In recent years, many studies have documented a lack of proficient critical thinking skills in college students (Holschuh, 2000; Weimer, 2002; Lord and Baviskar, 2007; Crowe et al., 2008; Lord, 2008; Stanger-Hall et al., 2010).
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This observation is in accordance with numerous other studies in the literature documenting a lack of cytotoxicity for nanoceria in various other cell lines38,39,40.
It should be emphasized that the studies documenting a lack of somatic mutations of HER2 in primary breast cancers [ 38] predate the development and use of Herceptin.
Over the past several years, there have been a number of high quality quantitative studies documenting a lack of access to health services and poorer health outcomes among Canadians experiencing homelessness [ 8– 11].
By using direct observation of the live animals, we documented a complete lack of the stimulated production of two vasodilative molecules, NO and H2O2, in response to muscle contraction: a possible cause of functional ischemia.
Using the AGREEII and ADAPTE guideline appraisal tools, Rohde et al, 15 documented a significant lack of high quality, comprehensive guidance for clinicians working with people with aphasia.
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