Since every interaction between the author and the document are mediated by visual abstractions, the validation tool may infer that the code generated by the authoring tool will always be syntactically correct, constraining the validation process to the semantic verification of the temporal synchronisms defined by the author.
The neuroblastoma progression linked to MYCN amplification, although well documented, is mediated by unknown molecular mechanisms.
Red deer have also been subjected to poorly documented human mediated translocations of animals, often over large distances, leading to mixing with or substitution of the indigenous population [ 6].
The possibility of geographic variation in population differentiation of parasitoids is very interesting considering the previously documented parasitoid mediated indirect interactions between G. tenella and G. calmariensis in northern localities.
GSTs are integral components of the cellular xenobiotic defense system [47] and have been documented to mediate allelochemical tolerance in terrestrial consumers [4] [6].
In support, the DMH sends marked projections to the septum and amygdala [55], [61], [64], and these telencephalic structures are well documented to mediate the affective or motivational component of various behaviors [65] [67].
These NRs have been documented to mediate repressive effects on inflammatory genes in an NCoR- and SMRT-dependent manner [76 78].
Several downstream targets, such as Bim, Bad, p53 and C-Jun, have been well documented to mediate the apoptotic effect of JNK activation.
Other factors, such as HLA-G, LIF and some others, are also documented to mediate the immunosuppression by human MSCs in vitro (Table 2).
In addition, they have also been documented to mediate abiotic plant responses to freezing [ 62], wounding [ 63], oxidative stress [ 64], drought, salinity, cold, and heat [ 65- 67].
Finally, the cells have been documented to mediate repair of damaged renal tissue in acute ischemic renal failure [ 16, 23, 24].
