This paper reviews documented disruption and physical damage of critical infrastructure elements resulting from four volcanic hazards (tephra fall, pyroclastic density currents, lava flows and lahars) of eruptions in the last 100 years.
Prior imaging studies have documented disruption in DAT (reviewed in [15]) as well as in the function and morphology of the ACG and the precuneus in subjects with ADHD [70] [72].
Based on our previous findings [2], [15] [18] and preclinical studies documenting disruption of dopaminergic pathways with repeated cocaine administration [19], [20], we hypothesized that hypoactive brain regions in cocaine abusers would also show lower functional connectivity with midbrain.
We found that although there are many other documented disruptions to the retinotopic map, often there were few quantitative characterizations of the data, though this may partly be due to the limitations of experimental techniques and the variability of phenotypes.
In particular, we could document that disruption of CFTR expression led to a higher cellular FA content characterized by an elevated proportion of saturated and n-7 FA.
Several studies of Vietnam veterans document the disruption of the family environment [ 3, 4], in parallel with a recent study of Cambodian refugee families investigating the relation between PTSD and long-term family dysfunction after Pol Pot [ 55].
Also, it has been documented that disruption of ATG7-mediated autophagy can evoke the interferon signaling pathway resulting in apoptosis of HCV-infected immortalized human hepatocytes (Shrivastava et al., 2011), and dramatically enhanced infectivity of human papillomavirus in primary human keratinocytes (Griffin et al., 2013).
It is well documented that disruption of the wnt pathway occurs early in the carcinogenesis process.
Despite this growing body of literature documenting endocrine disruption, much controversy remains about whether reproductive abnormalities observed in wild populations are caused by EDCs and not some other natural process.
However, it has been documented that disruption of the genes encoding COR can result in the accumulation of a chlorin with a HE group at C3 [31,32], indicating that BchF displays relaxed substrate specificity.
