Sentence examples for docking targeting from inspiring English sources
This resulted in a curated dataset of exactly 6094 compounds that were used for molecular docking targeting the HLA-B*57 01 HLA-B*57 01
As such, we believe that it is of the utmost importance that a thorough analysis of molecular docking targeting the HLA-B*57 01 HLA-B*57 01conducted in order to properly identify the limitations of this molecular modeling technique for forecasting a drug's likelihood to bind a HLA variant and thus potentially cause a HLA-mediated ADR.
In the current study, we have combined molecular docking targeted at the EGFR tetramer interface with a high throughput microscopy based screen to identify compounds that influence EGFR internalization, either independently or contingent upon the presence of EGF.
A total of 48 compounds were docked targeting the α-β interfacial site of tubulin heterodimer.
It was deliberate travel, slowed by a multitude of obstructions like antennas and docking targets.
The work went flawlessly, ending 16 minutes ahead of schedule even with the addition of a brief task, the manual extension of a docking target that did not properly deploy and was in the astronauts' way.
1, 1993 (Aug. 10, 1992 [Tognini]) crew performed spacewalks to extend lifetime of Mir Soyuz TM-16/Mir Russia Gennady Manakov; Aleksandr Poleshchuk Jan . 24 July 22 , 1993laced docking target on Mir for use by splacedhuttle Atlantis Soyuz TM-17/Mir Russia Vasily Tsibliyev; Aleksandockingbrov; Jean-Pierre Haigneré July 1, 1993–Jan.
Seventy percent of docking targets succeed when the unbound backbones is pushed to within 0.6 Å of the bound.
Therefore, we performed MD simulations for an Elk-1 ETS monomer, to generate an ensemble of monomeric ETS conformations to use as docking targets.
However, the experimental binding mode was reproduced successfully using members of the core ensemble as the docking target, establishing the usefulness of the method in drug design.
We are currently exploring these new tubulin models as docking targets.
