Sentence examples for docking sites on the from inspiring English sources

The yeast exocyst is a multiprotein complex comprised of eight subunits (Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84) which orchestrates trafficking of exocytic vesicles to specific docking sites on the plasma membrane during polarized secretion.

By adding GBV-C to H.I.V. in human blood cells in the laboratory, a team led by Dr. Jack T. Stapleton of the University of Iowa found that GBV-C blocked the docking sites on the CD-4 blood cell that H.I.V. needs to enter to cause infection.

This finding corroborates the fundamental role of surface GAGs to provide docking sites on the cell surface for heparin-binding growth factors (including VEGF-A).

Confirmed plasmid DNA (pJFRC-10xUAS-Otd FL with an attB integration site) was microinjected (2 μg/μl in 1× microinjection buffer) into Drosophila embryos that contain PhiC31 integrase and selected attP docking site on the second chromosome.

Note that the presence of an efficient attP docking site on the Y chromosome also can be used to integrate other markers that may allow optimal live labeling of male embryos and young larvae.

This activation of the ERK pathway is not dependent on the kinase activity of EGFR, but is mediated by docking sites on EGFR for Grb2, consistent with the notion that RTKs may also contribute to signal transduction by functioning as adaptor proteins (Yamauchi et al, 1997).

With knowledge of docking sites on HIV, small-molecule inhibitors might be developed to disrupt HIV protein phosphorylation by MAPKs, preventing HIV replication.

Following c-Met activation, an adaptor protein, Gab1, binds to cytoplasmic tyrosine docking sites on c-Met (Watanabe et al, 2006).

We further propose that the Prdx1 PTEN interaction is essential for protecting PTEN from oxidation-induced inactivation, as Prdx1 C- and N-terminal peptide replica, which were designed based on our mapping studies and computer modelling to block PTEN docking sites on Prdx1, resulted after H2O2 treatment in a 47% reduction of PTEN activity.

The BAF compounds in their computationally docked sites on Aβ fibers contact several (as few as three and as many as six) adjacent β-strands of the fiber.

The algorithm, named phospho-pivot modeling, consists of two parts: first is to generate a library of virtual complexes by pivoting phospho-ligand at the docking site on the receptor, and second is to grade them according to probability in atomic proximity between two molecules.