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Dok1 (docking protein 1) is phosphorylated by IR at specific tyrosine sites.
carcinoembryonic antigen-related cell adhesion molecule 1. docking protein 1. fatty acid-binding protein 4. fibroblast growth factor receptor substrate 2. growth factor receptor-bound.
Identification of the gene for NPHP type 1 had revealed nephrocystin as a novel docking protein, providing new insights into mechanisms of cell-cell and cell-matrix signaling.
The docking protein p130Cas becomes phosphorylated upon cell adhesion to extracellular matrix proteins, and is thought to play an essential role in cell transformation.
The aim of the study was to examine the localization of the botulinum toxin receptor element synaptic vesicle glycoprotein 2A (SV-2A) and the vesicular docking protein synaptosomal-associated protein 25 (SNAP25) in human and rat SPG.
Within the vesicle of the motor endplate it cleaves the vesicular docking protein SNAP-25, which leads to inhibition of acetylcholine storing vesicles docking on the presynaptic membrane and thus reduces acetylcholine release [8].
NEDD9 is a docking protein which plays a central co-ordinating role for tyrosine-kinase-based signalling related to cell adhesion.
The three genes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), transmembrane protein (Tmem) 111 and vesicle docking protein USO1 homolog (USO1) were used in PCR.
To investigate the effect of oligosaccharides on FGF2- or VEGF165- induced signalling events, we investigated changes in the phosphorylation state of FGFR docking protein FRS2, VEGFR-2, Erk and Akt.
In addition, XRCC3 did not alter the expression levels of the membrane form of KU80, another DNA repair-related gene (designated XRCC5) that functions as a docking protein for MMP-9 at the cell surface [16], [17], [33].
The first docking protein we identified was Munc18.
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