Sentence examples for docking defects from inspiring English sources

This model is consistent with findings in this current study and with our prior report on basal body migration, docking defects and defective actin organization upon loss of bbs8 and the PCP protein, vangl2 (42).

No docking defects were observed in synapses, in line with previous observations.

These observations concur with our previous work showing that nasal ciliated cells in Cby−/− mice have a paucity of motile cilia with apparent basal body docking defects [23].

Importantly, Syntaxin1-Munc18 interaction was not altered in synaptosomes from 1-month-old ASMko mice (Supplementary Figure S2B), in which vesicle docking defects are not yet significant.

The reviewers are right that future studies using cryo-fixation might unmask (subtle) docking defects upon CAPS loss.

Hence, general consensus exists on a post-synapse delivery role for CAPS but future studies using cryo-fixation might unmask (subtle) docking defects upon CAPS loss.

Instead of a docking defect, we observed an increase of docked vesicles at the active zone (Figure 4B), as previously observed in the Drosophila neuromuscular junction [5] and giant synapses of squid [29].

These small reductions in Munc18-1 levels appear to be insufficient to explain the drastic docking defect.

Thus, in contrast to chromaffin cells, synapses do not show a synaptic vesicle docking defect after syntaxin proteolysis.

Expression of BoNT/C shows the same docking defect as we previously found with Munc18-1 deletion [20], [24].

An impaired targeting or local accumulation of Munc18-1 at docking sites may therefore explain the docking defect in syntaxin-deleted chromaffin cells.