Exact(10)
The temporal variability in the amplitude of the diel DOC cycle was controlled by antecedent temperature.
Accordingly, 29 out of 44 registered patients (66%) went to DOC cycle.
During the DOC cycle, all patients received 8 mg of dexamethasone just before the administration of DOC.
Grade 3/4 neutropenia was seen in 36.3 and 39.4% in GEM/VNR and DOC cycle, respectively.
In all, 17 patients showed PR in the GE M/VNRcycle and four patients in the DOC cycle (data not shown).
A full dose of DOC was administrated on day 1 of the first DOC cycle, even if elevated toxicities were observed in the prior GE M/VNRcycles.
Similar(50)
The lower proportion of riparian peat downstream appeared to reduce the influence of terrestrial processes on DOC cycles.
DOC cycles in the 1st order stream had a median peak time of 14 00 h and temporally varying amplitude, with a median of 0.61 mg l−1.
Results supported the hypothesis that diel DOC cycles at the site are driven by hydrological processes, specifically the viscosity-effect theory: viscosity-driven increases in flow from the riparian area in the afternoon flush DOC from the peat to the stream.
In the DOC cycles, grade 3/4 neutropenia occurred in 39.4% but no patient experienced grade 3/4 anaemia or thrombocytopenia.
If WBC count was below 3000 mm−3 or platelet count was below 75 000 mm−3 at day 1 of the cycle, DOC administration was delayed by a week.
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