A key aspect of the behavior of any system is the timescale on which it operates: when inputs change, do responses take milliseconds, seconds, minutes, hours, days, months?
For example, do responses to items about career interests correlate with themselves highly, but correlate less with items focused on attitudes toward science, a dissimilar concept?
Collecting large amounts of in-depth data about participants, family members, and local communities also presents somewhat greater ethical challenges than do responses to closed-ended questions.
Several methodologies are progressing to clinical studies in humans but what do we know about the type of immune response offering protection from persistent HCV infection, and how do responses to the current vaccine candidates measure up against this ideal?
Comparison of item difficulty of the 30 final floor items (plain font) with PROMIS PF-10 items (bolded font) arranged from highest to lowest percent of "With Much Difficulty or Unable to Do" responses.
DO mice have been used previously in only two studies (Gopal et al., 2013; Harrison et al., 2014), but the breadth of DO responses to M. tuberculosis was not the focus.
