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This is largely due to the limited genetic resolution of an F2 cross, unless large numbers of mice are used, and the fact that standard F2 crosses do not interrogate all of the available genetic and phenotypic variance in the mouse genome.
The smaller probes are more sensitive to superficial epithelial tissue changes and demonstrate higher resistivity values at low frequencies but do not interrogate deeper sub-epithelial tissues well.
Yet, because Infinium I and Infinium II probes do not interrogate the same CpG population, the two types of probes are not expected to have the same distribution [ 3], and classic quantile normalization methods cannot be applied as such.
Do not interrogate the child or ask probing questions.
Similar(55)
To dream of a fluffier, easier, brighter-coloured world means you precisely don't interrogate its political contradictions.
It is thought that people don't interrogate their environment in these age.
Don't interrogate, just try to figure out what it's like to be him or her, doing that job and living that life.
Don't interrogate or interrupt.
"You don't interrogate your grandparents, right?" he laughed.
If you don't interrogate ethically and morally, the course teaches, the next person doesn't stand a chance.
This key theme is illustrated by the following quotations from R1: we don't interrogate clients when they come here.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com