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Together, the analysis in Figure 1 revealed that no other mutated genes in lung adenocarcinoma demonstrate such a strong mutually exclusive relationship, as do mutant KRAS and EGFR, further suggesting negative selection against the combination during lung tumorigenesis.
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Norrin disease-associated mutants V45E and L61P/A63D lose binding affinity for Fz4CRD, as do mutants R41E/H43E and R38E/R41S/H43E/K102E/K104E.
Along the same lines, does calcium depletion impact covalent modification of BiP? Second, do mutants in R470or R492, that prevent ADP-ribosylation, impact oligomerization?
Mutant mice of B6 background had higher cholesterol and phospholipid concentrations than did mutant mice of F1 or 129 backgrounds (p<0.01 to <0.001; Figure 6b, d).
Here, we similarly show that AP1 bacteria survived better inside differentiated HL-60 cells than did mutant BMJ71 bacteria, see Figure 3C.
How does mutant huntingtin enhance tumour aggressiveness?
Does mutant p53 bind to the IL-8 promoter?
Does mutant FUS misfold as we have seen for other ALS and neurodegenerative disease proteins?
However, in brains from patients with SCA3, mutant Ataxin3 accumulates in the nucleus [ 28, 89], as does mutant Ataxin1 [ 90].
"Why on earth did I do Teenage Mutant Turtles?" Ms. Walters said, looking back.
Do all mutant strains under all conditions always start at the same cell density?
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