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Although restriction enzymes were originally discovered for their ability to attack invading DNAs, it may be understood because such DNAs show deviation from this epigenetic status.
We note, however, that this suggestion does not provide a universal solution to all double-stranded DNAs; it deprives prokaryotes, centromere-less chromosomes, chromosomes with multiple centromeres, as well as double-stranded DNA viruses of their Watson and Crick strands, and does not even touch upon the problem of triple-stranded DNA, with its Watson, Crick and Hoogsteen strands [ 31].
In order to mitigate the effect of oxygen molecules on organellar DNAs, it would have been effective to both reduce the number of DNAs in the organellar genomes by gene transfer to the nucleus, and to compensate for mutations within organellar DNAs by RNA editing.
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And for LIFT, a theatre festival with internationalism seared into its DNA, it's especially bruising.
In DNA, it inhibits methylation by trapping DNA methyltransferase (Dnmt), resulting in its deactivation [ 43].
Once incorporated into DNA, it forms covalent complexes with DNMTs leading to inhibition of its activity, thereby decreasing DNA methylation.
You have no DNA — it's gone".
DNA, it is said, is the original software.
Then, assuming you've got a decent amount of clean DNA, it's ready to be analysed.
The final explanation, of course, comes from the dictates of hormones and DNA: it's the testosterone, stupid.
But -- here is the crucial difference -- unlike chromosomal DNA, it is not reshuffled when sperm meets egg.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com