Sentence examples for dna which causes from inspiring English sources
In this case, gold nanoparticles are uncovered owing to the formation of double-stranded DNA, which causes their aggregation upon addition of the salt, thereby leading to the change in the red-to-blue color.
Three main mechanisms are involved during the SODIS simultaneously, included the absorption of solar UV-B by microorganism DNA which causes direct damage by pyrimidine dimer formation.
A team in Glasgow says a faulty piece of DNA which causes leukaemia also has a role in some tumours and could help in research for new drugs.
Nuclear-targeting chemotherapeutics such as doxorubicin (DOX) kill cancer cells by intercalating with DNA, which causes disruption in replication and ultimately apoptosis.
PI dye selectively enters the cells with compromised membrane integrity and binds to the DNA which causes increase in the fluorescence intensity of PI dye, whereas in trypan blue dye exclusion assay live cell excludes the dye and dead cells stained with blue color.
MMS preferentially generates 3-methyladenine residues in DNA, which cause replication-fork arrest.
Platinum-based drugs can form intra- and inter-strand adducts with DNA, which cause DNA double-strand breaks and trigger DNA damage and repair pathways.
His laboratory has found that breaks in DNA, which cause relaxation of tightly wound chromatin, may be an important signal for activation of ataxia-telangiectasia-mutated kinase to initiate the cellular response to DNA damage.
As the control, the allele-specific PCR amplification was applied to genomic DNA, which caused equal amplification of ∗ 1 and ∗ 2. The allelic imbalance was evaluated in cells of culture cell lines, as well.
Exposure to cisplatin, an alkylating agent, results in the binding of cisplatin to DNA, forming cisplatin-DNA adducts which causes an alteration in the conformation of DNA leading to cell cycle arrest and apoptosis (Jordan and Carmo-Fonseca, 2000; Gonzalez et al, 2001; Wang et al, 2004).
Like other Top 1 inhibitors it exerts its mechanism of action through binding to the Top 1-DNA complex during replication and transcription and thereby maintaining single-strand DNA breaks, ultimately resulting in the formation of double-stranded DNA breaks, which causes cell death [ 24].
