Sentence examples for dna variation at from inspiring English sources

In linkage disequilibrium, one allele, a specific DNA variation at one site on the genome, occurs with another allele at a different site at a rate that is higher than expected by chance alone.

The investigation of DNA variation at loci fulfilling these criteria in natural populations of individuals related by descent [ 34] can lead to the detection of associations with positive or negative character values [ 35- 38].

Although in this study we identify novel DNA variation at the IL23A locus, we also demonstrate the highly conserved nature of IL23A, at both amino acid and predicted regulatory levels.

Focusing on commonly used genetic markers, we have analyzed both DNA sequences from the complete mitochondrial control region as well as nuclear DNA variation at ten microsatellite loci from these populations, sampled thrice in a 16 year time period, to develop a robust estimate of the population genetic history of these diversifying lineages.

The IMPROVE and WHII were genotyped using the Metabochip, a custom Illumina iSelect genotyping array that captures DNA variation at regions identified by meta-analyses of GWA studies for diseases and traits relevant to metabolic and atherosclerotic/cardiovascular endpoints, comprising approximately 200,000 SNPs.

DArT can detect and genotype DNA variations at several hundred genomic loci in parallel without relying on sequence information.

Some of them are mutations located within endonuclease restriction sites, others are single nucleotide polymorphisms (SNPs: DNA variations at a single nucleotide) or consist of insertions or deletions of larger fragments as detected by polymerase chain reaction technique (PCR) [ 9].

Thus, similar to infer the selection on DNA variations at the population level, intraspecific epimutation polymorphism spectrum could provide clues to detect the signature of natural selection on epialleles.

Finding such associations indicates that DNA variation, either at the candidate locus itself or at a linked locus is causal for the phenotypic variation.

The development of second generation sequencing methods has enabled large scale DNA variation studies at moderate cost.

Other studies have investigated microsatellite DNA variation, but only at local scales (see, for example, Say et al., 2003 in Ireland and Webley et al., 2007 in Australia).