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Malyarchuk BA, Grzybowski T, Derenko MV, Czarny J, Wozniak M, Miscicka-Sliwka D. Mitochondrial DNA variability in Poles and Russians.
Chloroplast microsatellite, or chloroplast simple sequence repeat (cpSSR), markers can be used to detect DNA variability in the chloroplast genome.
Fewer studies have focused on DNA variability in particular genomic segments, and even fewer have investigated variation beyond two or three population groups.
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Previous analyses on the correlation between mitochondrial DNA variability and longevity in humans have produced interesting but contradictory results (Passarino et al., 2010 and references therein).
Focusing on somatic mitochondrial DNA variability, F haplotypes detected in male soma (referred to as Fm) appeared to be significantly more variable than the ones detected in the female soma (here referred to as Ff; Fig. 2).
An association between DNA methylation and increasing age has also been reported, for example increased DNA methylation variability in older twins compared with younger twins and increasing variability with increasing age in familial clusters (37, 38).
Calafell F, Underhill P, Tolun A, Angelicheva D, Kalaydjie L. From Asia to Europe: mitochondrial DNA sequence variability in Bulgarians and Turks.
We have defined DNA repeat variability in the 3′-terminus of the cagA gene of Helicobacter pylori strains from Malaysian patients of different ethnicities.
Little is known about the impact of space (geography/ancestry) and time (age of the individuals) on DNA methylation variability in humans.
Environmental cardiovascular risk factors, such as smoking, a high-fat diet and physical activity, have been previously associated with DNA methylation variability in humans [ 19- 22].
The number of complementary binding sites on endogenous DNA is not expected to be directly proportional to the level of gene activation, primarily due to the nucleosome/histone packaging of DNA and variability in binding site availability.
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