Sentence examples for dna to regulate from inspiring English sources
The production of a genome-wide cis-regulatory map, indicating where transcription factors (TFs) bind genomic DNA to regulate gene expression, is critical to understanding gene regulation and genome function.
The editing technology relies on proteins known as zinc fingers, which bind to specific pieces of DNA to regulate nearby genes.
It can cut double-stranded DNA like Cas9, can bind to DNA to regulate genes, and it can be targeted to specific DNA sequences like other Cas proteins.
In the canonical pathway, steroid hormone binding to a nuclear receptor (NR), often in the cytoplasm, causes the receptor to undergo a conformational change and translocate to the nucleus, where it interacts with specific sequences of DNA to regulate transcription.
Next, GSH-bound PrfA will bind to the target DNA to regulate gene transcription.
Gene sequencing research that was published last week in the scientific journal Cell suggests that "junk" is capable of controlling important aspects of cell development, by showing how certain white blood cells use non-coding "junk" DNA to regulate the activity of genes in ways that determine their shape and function.
JUN directly interacts with specific target DNA sequences to regulate gene expression.
Finally, we use two orthogonal DNA handles to regulate two different bioactive signals, with the ability to independently up- or downregulate each over time.
Classic transcription factors (TFs) associate with histone and DNA modifiers to regulate the transcriptional activation or repression of their specific target genes1.
Like other nuclear receptors, RXRα has important genomic functions mainly through its binding to responding DNA elements to regulate target gene transcription (Tang and Gudas, 2011; Evans and Mangelsdorf, 2014).
The activation of cell growth and mTORC1 by E2F1 is dependent on both E2F1's ability to bind DNA and to regulate gene transcription, demonstrating that a gene induction expression program is required in this process.
