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The C2H2 domains bind to the DNA through a short alpha-helix domain and initiate transcription of target genes (Chang et al. 1996; Iuchi 2001).
Oxaliplatin adducts are lethal to cells, and may be removed from the DNA through a number of DNA repair pathways.
The first method, called "nanopore sequencing," involves pushing a strand of DNA through a tiny hole surrounded by sensors that detect the electrical changes caused by each DNA letter.
This confirms the capability for the direct detection of specific target DNA through a signal amplification process.
Storm, A. J., Chen, J. H., Zandbergen, H. W. & Dekker, C. Translocation of double-strand DNA through a silicon oxide nanopore.
Pulling a single strand of DNA through a nanopore allows researchers to potentially detect base pairs from just a single molecule.
O6-methylguanine-DNA methyltransferase (MGMT) ameliorates mutagenic, carcinogenic, and cytotoxic adducts from O6-methylguanine in DNA through a direct reversal mechanism.
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In a molecular docking model, compounds 9 and 15c interacted with Topo I-DNA through a different binding mode from 1 and 3.
LD studies indicated that the ruthenium complexes interact with ct-DNA through a mixed binding mode, which is influenced by complex concentration and chirality.
Running Courtney's Y-DNA through a vast database that contains the Y-DNA results of more than a half million men, turned up an identical match with a man named James Arrington, a doctor in Lewisville, Arkansas.
Infection requires the transfer of a small segment of DNA (the T-DNA), through a type IV secretion system, from a pathogen-encoded virulence plasmid into the plant genome.
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