Sentence examples for dna structures with from inspiring English sources
Curved DNA structures with a left-handed superhelical conformation can activate eukaryotic transcription.
But one of the challenges of the field is to find ways to design and engineer DNA structures with high precision.
Moreover, Ape1 cleaved AP sites in fork-like and bubble DNA structures with an efficiency that is identical or up to sevenfold higher than ssAP-DNA.
Several reports describe the generation of branched DNA structures with variable numbers of arms to self-assemble with pre-designed architectures.
To examine proper multivalency and type of aptamers in linear nucleic acid-based structures for efficient intracellular uptakes, we designed linear DNA structures with single and dual aptamers targeting guanosine-rich oligonucleotide 100 (AS1411) and mucin 1 (MUC-1).
In this review, we describe our efforts to create a form of gene-targeted radiation therapy by using the unique radiation effects of radionuclides that decay by the Auger process attached to oligonucleotide carrier-molecules that are capable of forming triplex DNA structures with target sequences in the genome of the human cancer cell.
And then, HP with a low melting temperature hybridized with designed SQS, forming a three-way DNA structure with an SQ.
Highest number of associations was observed for GGGGGT (4221), however, we noticed that this SES closely resembled a PG4 DNA sequence and hence was most likely to adopt a PG4 DNA structure with appropriate flanking sequence.
The ssDNA, dsDNA, DNA structure with bubble and AP sites located opposite the bulky lesions in dsDNA were used as substrates for Tdp1 (Fig. 1).
The stereoselectivity of 5 versus 1 was observed to be directly influenced by the DNA structure, with significantly greater levels of 5 being generated in ssDNA than dsDNA.
DNA glycosylases play a key role in the elimination of such DNA lesions; they recognize and excise damaged bases, thereby initiating a repair process that restores the regular DNA structure with high accuracy.
