Sentence examples for dna structures like from inspiring English sources

However, presence of non canonical sequences that can result in local non-B DNA structures like, G4 DNA has not been studied yet.

Protonation of NABs also contributes to stabilization of unusual DNA structures like triple helix, which is greatly stabilized at acidic pH, and knowledge about attachment of the proton is essential for the design of new intercalating drugs that stabilize the triple helix [21].

Enzymological and biological evidence from our laboratory suggests that DNMTs have evolved to recognize non-B DNA structures, like those associated with FRAXA in fragile X-linked mental retardation, and FRA11I/FRA11C in breast and prostate cancer [ 20, 107, 110], suggesting that DNMTs play an obligate role in the suppression of non-B DNA structures [ 116, 117] along with associated repair systems.

The repeat units of these minisatellites are mainly variants of the T nA mG o sequence and their evolutionary success presumably depends on their properties stemming from the G-rich sequence and their capacity to form alternative DNA structures like the G-quartet or the T-loop typical for telomere function (de Lange 2005).

For example, microsatellites composed of the motif AC/TG can absorb negative supercoiling through the formation of Z-DNA, which can displace nucleosomes (Liu et al. 2006; Zhang et al. 2006; Xu et al. 2011) and also prevent the formation of potentially hazardous non-B-DNA structures like slipped-strand DNA (Edwards et al. 2009).

It is now widely accepted that some tracks of genomic DNA that adopt non-canonical B-DNA structures like DNA-hairpin, cruciform, Z-DNA, triplex and tetraplex are represented as hotspots of chromosomal breaks, homologous recombination and gross chromosomal rearrangements [ 44].

See perpective article by K. Gothelf: "LEGO-like DNA structures".

Higher sensitivity of LAMP originates from the unique mechanism of amplification, known as loop-mediated amplification, which produces huge amplicons consisting of repeated loop-shaped and dumbbell-like DNA structures.

Hairpin- or cruciform-like DNA structures are strongly associated with genomic instability by their interference with DNA replication in both prokaryotes and eukaryotes.

(38) C-NHEJ causes formation of anaphase bridges, which are bridge-like DNA structures that span daughter chromosomes and frequently induce genomic instability through inappropriate chromosome segregation.

Due to their repetitive DNA sequence, unique architecture, bound shelterin proteins, and high propensity to form alternate/secondary DNA structures, telomeres are like common fragile sites and pose an inherent challenge to the progression of DNA replication, repair, and recombination apparatus.