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It does not indicate that DNA structure is not important to binding of these TFs to DNA.
"The DNA structure is one of those turning points," he says.
Therefore, the DNA structure is ideal for electron transfer due to hopping mechanism.
G-quadruplex DNA structure is considered to be a very attractive target for antitumor drug design due to its unique role in maintaining telomerase activities.
It is demonstrated that long-range coherent charge transport along the DNA structure is supported by mobile polaron and breather solutions, suggesting that DNA seems suitable for the design of functional nanostructures as ingredients in molecular nanoelectronic devices.
In the presence of monovalent Na+ ions, we find that the stretch modulus (γ1) of the paranemic crossover and its topoisomer JX DNA structure is significantly higher (∼30%) compared to normal B-DNA of the same sequence and length.
Similar(35)
The first Watson-Crick attempt to build a model of the DNA structure was a disaster.
DNA distortion was measured by calculating the root-mean-square deviation (rmsd) when each DNA structure was fitted onto its corresponding canonical A-DNA or B-DNA structure.
A control-PG4 DNA sequence (Text S1), which was very similar to the PG4 DNA motif but unlikely to adopt G4 DNA structure, was also used for analysis.
The effects on mutation frequency and alteration of DNA structure were compared.
DNA-metal and DNA-metal based complexes interactions and their effect on DNA structure are already known [ 22– 29].
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