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It is proposed that a DNA stabilizing solution (DNA Genotek Inc).
DNA stabilizing solution enables the storage and transportation of swabs without freezing.
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Let X be the stabilizing solution of (1a - 1b).
Samples were collected in tubes containing RNA stabilizing solution (Applied Biosystems, Life Technologies Corporation).
A fragment of each sample was preserved for transcriptomic analysis in an RNA stabilizing solution.
This motif forms the equatorial interface, and presumably the interaction with DNA stabilizes this structural element.
Mechanistically, PHF20L1 might participate in regulating DNA methylation by stabilizing DNA methyltransferase 1 (DNMT1) protein in breast cancer.
In phase II trial, cecatecarin (570) intercalates into DNA and stabilizes the DNA-topoisomerase I complex, thereby interfering with the topoisomerase I-catalyzed DNA breakage-reunion reaction and initiating DNA cleavage and apoptosis [293].
Optimization strategies must therefore include some way of stabilizing the solutions.
Moreover, SIRT6 is required for mobilization of the DNA-PK catalytic subunit (DNA-PKcs) to chromatin in response to DNA damage and stabilizes DNA-PKcs at chromatin adjacent to an induced site-specific DSB.
Segurado, M. & Diffley, J. Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks.
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